PD 132002 [CAS 134452-04-3]

PD 132002 is an orally active, potent renin inhibitor. PD 132002 weakly inhibits pepsin. PD 132002 produces substantial reductions in blood pressure[1].

[134452-04-3]

C31H50N4O9S

654.82

O=C(C(NC([C@@H](NS(=O)(N1CCOCC1)=O)CC2=CC=CC=C2)=O)C(OC)=O)N[C@H]([C@@H](O)[C@@H](O)CC(C)C)CC3CCCCC3

Renin

10 mM in DMSO

Room temperature