PD 144418 [CAS 154130-99-1]

PD 144418 is a highly affinity, potent and selective sigma 1 (σ1) receptor ligand (Ki values of 0.08 nM and 1377 nM for σ1 and σ2 respectively) . PD 144418 devoids of any significant affinity for other receptors, ion channels and enzymes. PD 144418 shows potential antipsychotic activity[1][2].

[154130-99-1]

C18H22N2O

282.38

CCCN1CC(C2=CC(C3=CC=C(C)C=C3)=NO2)=CCC1

Sigma Receptor

Sigma 1 Receptor

98.32

DMSO : 125 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature