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SKU:QM-0155507-01
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PD151746 is a calpain inhibitor, shows a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM) . IC50 value: 0.26 ± 0.03 μM (Ki, for μ-calpain), 5.33 ± 0.77 μM (Ki, for m-calpain) [1] Target: calpain in vitro: The μ-calpain inhibitor PD 151746 decreases oxLDL-induced cytotoxicity. [2]
[181765-30-0]
C11H8FNO2S
237.25
O=C(O)/C(S)=C/C1=CNC2=C1C=C(F)C=C2
Proteasome
10mM
95.03
DMSO : 50 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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PD 151746 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.