PDEB1-IN-1 [CAS 1622300-88-2]

PDEB1-IN-1 (Compound 12b) is the derivative of Cilomilast , and serves as an inhibitor for TryPanosoma Brucei PDEB1 (TbrPDEB1) with an IC50 of 0.95 μM. PDEB1-IN-1 inhibits the proliferation of T. Brucei with an EC50 of 26 μM[1].

[1622300-88-2]

C25H29NO5

423.5

N#C[C@]1(C2=CC(OCCCCOC3=CC=CC=C3)=C(C=C2)OC)CC[C@@H](CC1)C(O)=O

Parasite

Room temperature