Pegloxenatide [CAS 2420483-82-3]

Pegloxenatide (Polyethylene glycol loxenatide) is a long-acting glucagon-like peptide-1 receptor (GLP-1RA) agonist. Pegloxenatide has various activities such as lowering blood glucose, lowering blood lipids, improving body weight, anti-inflammation, promoting wound healing, protecting the liver, and protecting the heart. Pegloxenatide can be used in the research of type 2 diabetes and its multiple complications[1][2][3][4].

[2420483-82-3]

(C2H4O) n (C2H4O) nC206H317N55O67S

[PEGn-H-{D-Ala}-EGTFTSDLSKQ-{Nle}-EEEAVRLFIEWLKQGGPSSGAPPPC-NH2]

Akt; AMPK; Apoptosis; Autophagy; GCGR; Interleukin Related; PI3K; Reactive Oxygen Species (ROS) ; Sirtuin

90

10 mM in DMSO

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature