Periglaucine B [CAS 1025023-05-5]

Periglaucine B ((+) -Periglaucine B) is an alkaloid and an HBsAg inhibitor. Periglaucine B can be isolated from Pericampylus glaucus. Periglaucine B inhibits the secretion of hepatitis B virus (HBV) surface antigen (HBsAg) in Hep G2.2.15 cells with an IC50 of 0.47 mM[1].

[1025023-05-5]

C20H23NO6

373.4

CO[C@]1(O[C@@]([H])(C2)C3=CC4=C(OCO4)C=C3[C@@](CC5=O)(CC6)[C@]12N6C)[C@H]5OC

HBV

10 mM in DMSO

Room temperature