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PERK-IN-5 [CAS 2616821-91-9]
PERK-IN-5 [CAS 2616821-91-9]
SKU:QM-0148750-01
£633.20 GBP
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Product Details
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Description
PERK-IN-5 is a highly potent, selectively and orally bioavailable PERK inhibitor (IC50s of 2 and 9 nM for PERK and p-eIF2α, respectively) . PERK-IN-5 can significantly inhibit tumor growth in the 786-O renal cell carcinoma xenograft tumor model[1].
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CAS Number
[2616821-91-9]
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Molecular Formula
C25H26F2N4O3
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Molecular Weight
468.5
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Smiles
CCC1=C(C2=CN=C(N)C(C(NC(C)C)=O)=C2)C=CC(NC([C@@H](C3=CC(F)=CC(F)=C3)O)=O)=C1
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Target
PERK
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Concentration
10mM
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Purity
99.4
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Solubility
DMSO : 250 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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PERK-IN-5 [CAS 2616821-91-9]
PERK-IN-5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.