PF-04859989 [CAS 34783-48-7]

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SKU:QM-0125563

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Product Details

Description
PF-04859989 is a brain-penetrant, irreversible kynurenine aminotransferase (KAT) II inhibitor with IC50s of 23 and 263 nM for hKAT II and rKAT II. PF-04859989 is selective for KAT II over human KAT I, KAT III, and KAT IV (IC50s of 22, 11, and >50 μM, respectively) [1].
CAS Number
[34783-48-7]
Molecular Formula
C9H10N2O2
Molecular Weight
178.19
Smiles
O=C1N(O)C2=C(C=CC=C2)C[C@@H]1N
Target
Aminotransferases (Transaminases)
Shipping Conditions
Room temperature
Hazard Statement
H302-H315-H319-H332-H335
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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PF-04859989 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.