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SKU:QM-0081784-01
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PF-05085727 is a potent, selective and brain penetrant inhibitor of cGMP-dependent PDE2A (IC50=2 nM) . PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11[1].
[1415637-72-7]
C20H18F3N7
413.4
CN1C2=NC=NC(N3CCC3)=C2C(C4=C(C5=CC=C(C(F)(F)F)C=C5)N(C)N=C4)=N1
Phosphodiesterase (PDE)
PDE2
10mM
99.53
DMSO : 62.5 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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PF-05085727 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.