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SKU:QM-0077966-01
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PF-05214030 is a TRPV4 antagonist (IC50: 4 and 27nM for hTRPV4 and rTRPV4 respectively) . PF-05214030 reverses the reduction in bladder capacity caused by intravesical infusion of a TRPV4 agonist[1][2].
[1669444-50-1]
C17H13Cl2FN2O4S
431.27
N#CC1=CC=C(C=C1F)OCC2(CN(S(=O)(C3=CC=C(C=C3Cl)Cl)=O)C2)O
TRP Channel
TRPV4
99.81
DMSO : 200 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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PF-05214030 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.