PF-06726304 (acetate) [CAS 2080306-28-9]

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SKU:QM-0057417

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Description
PF-06726304 acetate is a potent and selective EZH2 inhibitor. PF-06726304 acetate inhibits wild-type and Y641N mutant EZH2 with Kis of 0.7 and 3.0 nM, respectively. PF-06726304 acetate displays robust antitumor growth activity[1].
CAS Number
[2080306-28-9]
Molecular Formula
C24H25Cl2N3O5
Molecular Weight
506.38
Smiles
O=C1N(CC2=C(C)C=C(C)NC2=O)CCC3=C1C(Cl)=C(C4=C(C)ON=C4C)C=C3Cl.CC(O)=O
Target
Histone Methyltransferase
Isoform
EZH2
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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PF-06726304 (acetate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.