PF-06835919 [CAS 2102501-84-6]

PF-06835919 (Ketohexokinase inhibitor 1) is an inhibitor of ketohexokinase (KHK), with IC50s of 8.4 nM and 66 nM for KHK-C and KHK-A, respectively. PF-06835919 can be used for the study of metabolic disorders driven by the overconsumption of Fructose[2].

[2102501-84-6]

C16H19F3N4O2

356.34

O=C(C[C@H]1[C@@]2(CN(C[C@]12[H])C3=NC(N4[C@H](CC4)C)=NC(C(F)(F)F)=C3)[H])O

Ketohexokinase

99.53

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years (Powder)

Blue Ice

H302-H315-H319-H335

P261-P280-P302+P352