PF-06843195 [CAS 2067281-51-8]

Name: PF-06843195 [CAS 2067281-51-8]
Brand: QuantiMol
SKU: QM-0143790-01
Price: 118.38 GBP
Availability: InStock

Size 5 mg 10 mM - 1 mL 10 mg

SKU:QM-0143790-01

£118.38 GBP

Sale Sold out

Quote Datasheet SDS COA

Product Details

Description
PF-06843195 is a highly selective PI3Kα inhibitor with an IC50 of 18 nM in Rat1 fibroblasts. The Kis of PF-06843195 for PI3Kα and PI3Kδ in biochemical kinase assay are less than 0.018 nM and 0.28 nM, respectively. PF-06843195 has great suppression of the PI3K/mTOR signaling pathway and durable antitumor efficacy[1].
CAS Number
[2067281-51-8]
Molecular Formula
C20H25F3N8O4
Molecular Weight
498.46
Smiles
OC[C@]1(CN(CC1)C(OCC(F)F)=O)NC2=NC(N3CCOCC3)=NC(C4=CN=C(N)N=C4)=C2F
Target
PI3K
Isoform
PI3Kα; PI3Kβ; PI3Kδ
Purity
98.12
Solubility
DMSO : 60 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

Your cart
Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0143790-01	5 mgQM-0143790-01 £118.38/ea	£0.00	Quantity	£118.38/ea	£0.00

10 mM - 1 mLQM-0143790-02	10 mM - 1 mLQM-0143790-02 £127.38/ea	£0.00	Quantity	£127.38/ea	£0.00

10 mgQM-0143790-03	10 mgQM-0143790-03 £238.32/ea	£0.00	Quantity	£238.32/ea	£0.00

Total items

£0.00

Product subtotal

Taxes, discounts and shipping calculated at checkout.

PF-06843195 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.