Pfn1-IN-2 [CAS 919010-22-3]

Pfn1-IN-2 is an inhibitor of Profilin1 (Pfn1) and has the activity to interfere with the interaction between Pfn1 and actin. Pfn1-IN-2 can significantly reduce the overall level of intracellular filamentous (F) actin. Pfn1-IN-2 also slows down the migration and proliferation of endothelial cells (EC) . Pfn1-IN-2 can inhibit the angiogenic ability of endothelial cells both in vivo and in vitro[1].

[919010-22-3]

C18H13N7O2

359.34

O=C1NN=C(C2=C1NC3=NN=NN3C2C4=CC=CC(O)=C4)C5=CC=CC=C5

Endogenous Metabolite

Room temperature