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PHA-665752 [CAS 477575-56-7]

PHA-665752 [CAS 477575-56-7]

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QM-0136912-01

£111.63 GBP
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Product Details

  • Description

    PHA-665752 is a selective, ATP-competitive, and active-site inhibitor of the catalytic activity of c-Met kinase (Ki=4 nM; IC50=9 nM) . PHA-665752 exhibits >50-fold selectivity for c-Met compared with a panel of diverse tyrosine and serine-threonine kinases. PHA-665752 induces apoptosis and cell cycle arrest, and exhibits cytoreductive antitumor activity[1][2].

  • CAS Number

    [477575-56-7]

  • Molecular Formula

    C32H34Cl2N4O4S

  • Molecular Weight

    641.61

  • Smiles

    O=C(C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)S(=O)(CC4=C(C=CC=C4Cl)Cl)=O)=O)=C1C)C)N5[C@H](CCC5)CN6CCCC6

  • Target

    Apoptosis; Autophagy; c-Met/HGFR

  • Concentration

    10mM

  • Purity

    99.85

  • Solubility

    DMSO : 25 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0136912-01
5 mgQM-0136912-01
£111.63/ea		 £0.00
£111.63/ea £0.00
10 mM - 1 mLQM-0136912-02
10 mM - 1 mLQM-0136912-02
£148.75/ea		 £0.00
£148.75/ea £0.00
10 mgQM-0136912-03
10 mgQM-0136912-03
£194.59/ea		 £0.00
£194.59/ea £0.00
25 mgQM-0136912-04
25 mgQM-0136912-04
£339.17/ea		 £0.00
£339.17/ea £0.00
50 mgQM-0136912-05
50 mgQM-0136912-05
£508.06/ea		 £0.00
£508.06/ea £0.00
100 mgQM-0136912-06
100 mgQM-0136912-06
£791.15/ea		 £0.00
£791.15/ea £0.00
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PHA-665752 [CAS 477575-56-7]

PHA-665752 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.