PHGDH-IN-6

PHGDH-IN-6 (Compound L5) is a PHGDH allosteric inhibitor with an IC50 of 2.5 μM. PHGDH-IN-6 can be used for studying diseases related to serine synthesis[1].

C33H28BrN3O8

674.49

BrC1=CC(C#CC2=CC=C(NC(C3=C(NC([C@]45C[C@H](NC(OC(C)(C)C)=O)C(O5)=O)=O)C4=CC=C3)=O)C=C2)=CC(C(OC)=O)=C1

Phosphoglycerate Dehydrogenase (PHGDH)

Room temperature