PhoPS

PhoPS is the photocaged inhibitor for β-lactamase. PhoPS is activated upon light irradiation, and active β-lactamase inhibitor Sulbactam is released. PhoPS inhibits the synthesis of bacterial cell wall and the formation of E. coli biofilm, exhibits antimicrobial activity[1].

C42H57N5O17S

935.99

CC(COC(C(C1(C)C)N2C(CC2=O)S1(=O)=O)=O)C3=C([N+]([O-])=O)C=CC(C4=CC=C(OCCOCCOCCOCCN5N=NC=C5CCCO[C@@H]6O[C@H](CO)[C@@H]([C@@H]([C@H]6O)O)O)C=C4)=C3

Bacterial; Beta-lactamase

Room temperature