Phosphoramidon (disodium) [CAS 164204-38-0]

Phosphoramidon disodium, a microbial metabolite, is a specific metalloprotease thermolysin inhibitor with an IC50 of 0.4 μg/mL. Phosphoramidon disodium also inhibits endothelin-converting enzyme (ECE), neutral endopeptidase (NEP), and angiotensin-converting enzyme (ACE) with IC50 values of 3.5, 0.034, and 78 μM, respectively[1][2][3].

[164204-38-0]

C23H32N3Na2O10P

587.47

O=C([C@@H](NC([C@@H](NP(O[C@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](O1)C)(O[Na])=O)CC(C)C)=O)CC2=CNC3=CC=CC=C23)O[Na]

Angiotensin-converting Enzyme (ACE) ; Endogenous Metabolite; MMP; Neprilysin

Microbial Metabolite

99.83

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 140 mg/mL

4°C (Powder, sealed storage, away from moisture)

Room Temperature