PhpC is a G-quadruplex (G4) -DNA/RNA disruptor. PhpC disrupts DNA and RNA G4 structures and promotes G4 helicase activity. PhpC effectively enhancing the activity of Taq polymerase. PhpC modulates G-quadruplexs (G4s) both in vitro and in cells[1][2][3].
Molecular Formula
C18H20N4O4
Molecular Weight
356.38
Smiles
NCCOC1=CC=CC(C2=CC3=CN(C(N=C3N2)=O)CC(OCC)=O)=C1
Target
DNA/RNA Synthesis; G-quadruplex
Purity
98.9
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
