Phthalimide-PEG4-PDM-OTBS

Size 1 Each

SKU:QM-0061311

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Product Details

Description
Phthalimide-PEG4-PDM-OTBS is a PROTAC linker, which refers to the PEGs composition. Phthalimide-PEG4-PDM-OTBS can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Molecular Formula
C27H44N2O7Si
Molecular Weight
536.73
Smiles
O=C(N1CCOCCOCCOCCO[C@@H]2C[C@@H](CO[Si](C(C)(C)C)(C)C)NC2)C3=C(C=CC=C3)C1=O
Target
PROTAC Linkers
Isoform
PEG Linkers
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature
Hazard Statement
H302-H315-H319-H335
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Variant	Variant total	Quantity	Price	Variant total
1 EachQM-0061311	1 EachQM-0061311 £0.00/ea	£0.00	Quantity	£0.00/ea	£0.00

Phthalimide-PEG4-PDM-OTBS is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.