Phyllodulcin [CAS 21499-23-0]

Phyllodulcin is an orally active sweetener found in Hydrangea macrophylla var. thunbergii. Phyllodulcin acts as a non-selective phosphodiesterase inhibitor and exerts anti-allergic effects by suppressing lymphocyte activation. Phyllodulcin can be used to combat obesity by regulating levels of leptin, fat browning-related genes, and hypothalamic BDNF-TrkB signaling[1][2].

[21499-23-0]

C16H14O5

286.28

COC1=C(C=C(C=C1)[C@H]2CC3=C(C(=CC=C3)O)C(=O)O2)O

Phosphodiesterase (PDE)

10mM

99.75

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, stored under nitrogen)

Room Temperature

H302, H315, H319

H302, H315, H319