Physalin A [CAS 23027-91-0]

Physalin A is a biologically active withanolide. Physalin A shows anti-inflammatory, antifibrotic and ameliorative effects on autophagy in models of disc degeneration. Physalin A has antitumor activity and can induce apoptosis, ROS production and G2/M phase cell cycle arrest. Besides. Physalin A can significantly increase the activity of quinone reductase and increase the expression of detoxifying enzymesc[1][2][3][4].

[23027-91-0]

C28H30O10

526.53

C[C@@]([C@@](OC1=O)([H])C2)(OC3=O)[C@@]([C@@]3(CC[C@@]([C@]45C)([H])[C@@]6([H])[C@@H](C=C4CC=CC5=O)O)O)(O[C@@]76O)[C@](C7=O)([H])[C@]2(C1=C)C

Akt; Apoptosis; Autophagy; JAK; mTOR; NF-κB; p38 MAPK; PI3K; STAT

99.63

10 mM in DMSO

4°C (Powder, protect from light)

Room Temperature