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PI-1840 [CAS 1401223-22-0]

PI-1840 [CAS 1401223-22-0]

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QM-0140687-01

£94.75 GBP
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Product Details

  • Description

    PI-1840 is a potent and selective chymotrypsin-like (CT-L) inhibitor for with an IC50 value of 27 nM. PI-1840 inhibits cell proliferation and arrest cell cycle at G2/M phase. PI-1840 induces apoptosis and induces autophagy. PI-1840 induces the accumulation of proteasome substrates p27, Bax, and IκB-α[1][2].

  • CAS Number

    [1401223-22-0]

  • Molecular Formula

    C22H26N4O3

  • Molecular Weight

    394.47

  • Smiles

    O=C(N(C(C)C)CC1=NC(C2=CC=CN=C2)=NO1)COC3=CC=C(CCC)C=C3

  • Target

    Apoptosis; Autophagy; Bcl-2 Family; Caspase; NF-κB; PARP; Proteasome

  • Purity

    98.78

  • Solubility

    DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H317-H319

  • Precautions

    P261-P264-P272-P280-P302+P352-P305+P351+P338-P362+P364-P501
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Variant Variant total Quantity Price Variant total
5 mgQM-0140687-01
5 mgQM-0140687-01
£94.75/ea		 £0.00
£94.75/ea £0.00
10 mM - 1 mLQM-0140687-02
10 mM - 1 mLQM-0140687-02
£101.50/ea		 £0.00
£101.50/ea £0.00
10 mgQM-0140687-03
10 mgQM-0140687-03
£136.38/ea		 £0.00
£136.38/ea £0.00
25 mgQM-0140687-04
25 mgQM-0140687-04
£290.57/ea		 £0.00
£290.57/ea £0.00
50 mgQM-0140687-05
50 mgQM-0140687-05
£424.22/ea		 £0.00
£424.22/ea £0.00
100 mgQM-0140687-06
100 mgQM-0140687-06
£611.33/ea		 £0.00
£611.33/ea £0.00
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PI-1840 [CAS 1401223-22-0]

PI-1840 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.