PI5P4Kγ-IN-1 [CAS 2419358-87-3]
PI5P4Kγ-IN-1 [CAS 2419358-87-3]
SKU:QM-0077514-01
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Product Details
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Description
PI5P4Kγ-IN-1 (compound 2) is a selective PI5P4Kγ inhibitor. PI5P4Kγ-IN-1 can be used to signal mTORC1 in MCF-7 breast cancer cells and further characterize PI5P4Kγ in the cells[1].
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CAS Number
[2419358-87-3]
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Molecular Formula
C20H20N4O
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Molecular Weight
332.4
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Smiles
NC1=NC(C2=C(CCC3)NC4=C2C=C(C5=CCOCC5)C=C4)=C3C=N1
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Target
PI5P4K
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Purity
98.82
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H319, H320
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Precautions
P264, P280, P302+P352, P305+P351+P338, P362
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PI5P4Kγ-IN-1 [CAS 2419358-87-3]
PI5P4Kγ-IN-1 for PI5P4Kγ and mTORC1 Signaling Research
PI5P4Kγ-IN-1, CAS 2419358-87-3, is supplied for laboratory workflows involving PI5P4Kγ/PIP4K2C pathway studies, chemical probe evaluation, and cell-signaling method development.
Research context
PI5P4Kγ-IN-1 is used in research settings where teams need a small-molecule tool for studying phosphatidylinositol-5-phosphate 4-kinase gamma biology. It is relevant to workflows examining PI5P4Kγ, PIP4K family signaling, mTORC1 pathway readouts, and MCF-7 cell signaling models.
Key identity references
| Compound | PI5P4Kγ-IN-1 |
|---|---|
| CAS number | 2419358-87-3 |
| Molecular formula | C20H20N4O |
| Molecular weight | 332.4 |
| Application field | PI5P4Kγ/PIP4K signaling, lipid kinase pathway research, and mTORC1-related cell-signaling studies. |
How researchers use this compound
Pathway interrogation
Used in PI5P4Kγ-focused workflows to explore how PIP4K family signaling connects with mTORC1 pathway readouts.
Cell-signaling experiments
Relevant for method development in cellular models where PI5P4Kγ biology, mTORC1 signaling, or PIP4K2C-related responses are under investigation.
Chemical probe comparison
May be used as part of structured comparison panels alongside appropriate inactive controls, orthogonal assays, and matched vehicle controls.
Analytical preparation
Suitable for laboratory preparation workflows using validated solvent handling, controlled storage, and batch documentation.
Selection notes for laboratory teams
- Confirm the CAS number, formula, lot purity, and analytical documentation against the current QuantiMol CoA before use.
- Use the native solubility guidance as a starting point only; confirm practical solubility under the exact assay conditions.
- For cell-based work, include vehicle-only controls and concentration-response planning appropriate to the model system.
- Store powder and prepared solutions according to the product label and batch-specific documentation.
Safety and handling note
| Hazard statements listed on native page | H315, H319, H320 |
|---|---|
| Precautionary statements | The native page currently repeats H statements in the precautions field. Confirm correct P-phrase precautions against the batch-specific SDS before use. |
| Handling approach | Handle only in an appropriately equipped laboratory using trained personnel, suitable PPE, and local chemical hygiene procedures. |
Safety classifications for research chemicals can vary by batch, concentration, jurisdiction, and SDS version. Confirm against batch-specific SDS.
Neutral reference resources
Useful non-supplier references include PubChem, NIH / PubMed Central literature on PI5P4Kγ chemical probe research, ECHA chemical information, and UNECE GHS guidance.
FAQ
What is PI5P4Kγ-IN-1 used for?
PI5P4Kγ-IN-1 is used in laboratory research workflows studying PI5P4Kγ, PIP4K signaling, and mTORC1-related pathway readouts.
What is the CAS number of PI5P4Kγ-IN-1?
The CAS number of PI5P4Kγ-IN-1 is 2419358-87-3.
What is the molecular formula of PI5P4Kγ-IN-1?
The molecular formula of PI5P4Kγ-IN-1 is C20H20N4O.
What is the molecular weight of PI5P4Kγ-IN-1?
The molecular weight listed for PI5P4Kγ-IN-1 is 332.4.
Is PI5P4Kγ-IN-1 related to mTORC1 signaling research?
Yes. PI5P4Kγ-IN-1 is relevant to research workflows examining PI5P4Kγ and mTORC1 signaling readouts in cell-based systems.
Is PI5P4Kγ-IN-1 for research use only?
Yes. PI5P4Kγ-IN-1 is for laboratory research use only and is not intended for human, veterinary, food, drug, or household use.