Pilabactam [CAS 2410688-60-5]

Pilabactam (ANT3310) is a broad-spectrum covalent Serine β-Lactamase inhibitor, with IC50 values ranging from 1 nM to 175 nM (a panel of Serine β-Lactamase) . Pilabactam potentiates activity of β-lactam antibiotics against Carbapenem-Resistant Enterobacterales (CRE) and Acinetobacter baumannii (CRAB) . Pilabactam can be used in the research of bacterial infection[1][2].

[2410688-60-5]

C6H9FN2O5S

240.21

O=S(ON1[C@H]2C[N@]([C@@H](CC2)F)C1=O)(O)=O

Bacterial; Beta-lactamase

10 mM in DMSO

Room temperature