Pimicotinib [CAS 2253123-16-7]

Pimicotinib (ABSK021) is a selective and orally active CSF1R inhibitor with an IC50 value of 19.48 nM (determined by inhibiting ADP production) . Pimicotinib exhibits anti-tumor activity[1][2][3].

[2253123-16-7]

C22H24N6O3

420.46

O=C(N1C(C(C)(CC1)C)=O)NC2=CC=C(OC3=CC=NC(C4=CN(C)N=C4)=C3)C(C)=N2

C-Fms; c-Kit; PDGFR

99.92

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature