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Pimozide-d5 N-Oxide [CAS 1794795-40-6]
Pimozide-d5 N-Oxide [CAS 1794795-40-6]
SKU:QM-0142973-01
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Product Details
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Description
Pimozide-d5 N-Oxide is the deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist, with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozide also inhibits STAT3 and STAT5[1][2].
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CAS Number
[1794795-40-6]
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Molecular Formula
C28H24D5F2N3O2
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Molecular Weight
482.58
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Smiles
O=C1N(C=2C(N1)=CC=CC2)C3(C(CN(CCCC(C4=CC=C(F)C=C4)C5=CC=C(F)C=C5)(=O)CC3([2H])[2H])([2H])[2H])[2H]
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Target
Adrenergic Receptor; Dopamine Receptor; Isotope-Labeled Compounds; STAT
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Isoform
D1 Receptor; D3 Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Pimozide-d5 N-Oxide [CAS 1794795-40-6]
Pimozide-d5 N-Oxide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.