Pioglitazone (U 72107) is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone can be used in diabetes research[2][3][4].
CAS Number
[111025-46-8]
Molecular Formula
C19H20N2O3S
Molecular Weight
356.44
Smiles
O=C(N1)SC(CC2=CC=C(OCCC3=NC=C(CC)C=C3)C=C2)C1=O
Target
Ferroptosis; PPAR
Isoform
PPARα; PPARβ/δ; PPARγ
Concentration
10mM
Purity
99.89
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)