Piribedil (maleate) [CAS 937719-94-3]

Piribedil maleate is a potent and orally active dopamine D2 and dopamine D3 agonist. Piribedil maleate is also a α2-adrenoceptors antagonist. Piribedil maleate can inhibit MLL1 methyltransferase activity (EC50: 0.18 μM) . Piribedil maleate has the potential for the research of parkinson's disease, circulatory disorders, cancers[1][2][3][4].

[937719-94-3]

C20H22N4O6

414.41

O=C(/C=C\C(O)=O)O.C1(N2CCN(CC2)CC3=CC=C4OCOC4=C3)=NC=CC=N1

Adrenergic Receptor; Dopamine Receptor; Histone Methyltransferase

Room temperature