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Pirtobrutinib [CAS 2101700-15-4]

Pirtobrutinib [CAS 2101700-15-4]

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QM-0075516-01

£129.63 GBP
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Product Details

  • Description

    Pirtobrutinib (LOXO-305), a highly selective and non-covalent next generation BTK inhibitor, inhibits diverse BTK C481 substitution mutations. Pirtobrutinib causes regression of BTK-dependent lymphoma tumors in mouse xenograft models. Pirtobrutinib is also more than 300-fold selective for BTK versus 370 other kinases tested and shows no significant inhibition of non-kinase off-targets at 1 μM[1].

  • CAS Number

    [2101700-15-4]

  • Molecular Formula

    C22H21F4N5O3

  • Molecular Weight

    479.43

  • Smiles

    O=C(C1=C(N)N([C@@H](C)C(F)(F)F)N=C1C2=CC=C(CNC(C3=CC(F)=CC=C3OC)=O)C=C2)N

  • Target

    Btk

  • Purity

    99.9

  • Solubility

    DMSO : 50 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, stored under nitrogen)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0075516-01
5 mgQM-0075516-01
£129.63/ea		 £0.00
£129.63/ea £0.00
10 mM - 1 mLQM-0075516-02
10 mM - 1 mLQM-0075516-02
£135.25/ea		 £0.00
£135.25/ea £0.00
10 mgQM-0075516-03
10 mgQM-0075516-03
£250.47/ea		 £0.00
£250.47/ea £0.00
25 mgQM-0075516-04
25 mgQM-0075516-04
£514.13/ea		 £0.00
£514.13/ea £0.00
50 mgQM-0075516-05
50 mgQM-0075516-05
£753.49/ea		 £0.00
£753.49/ea £0.00
100 mgQM-0075516-06
100 mgQM-0075516-06
£1,166.59/ea		 £0.00
£1,166.59/ea £0.00
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Pirtobrutinib [CAS 2101700-15-4]

Pirtobrutinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.