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SKU:QM-0083120-01
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PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo[1].
[53501-41-0]
C14H10ClN3O4S
351.76
O=C(NC(NC1=CC([N+]([O-])=O)=CC(Cl)=C1O)=S)C2=CC=CC=C2
PI3K
98.56
DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)
4°C (Powder, protect from light)
Room Temperature
H302, H400
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PIT-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.