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PKC-IN-4 [CAS 2636771-29-2]
PKC-IN-4 [CAS 2636771-29-2]
SKU:QM-0067505
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Product Details
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Description
PKC-IN-4 (compound 7l) is a potent and orally active aPKC inhibitor with an IC50 of 0.52 μM. PKC-IN-4 inhibits TNF-α induced NF-κB activity in vitro. PKC-IN-4 blocks VEGF- and TNFα-induced permeability across the retinal vasculature[1].
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CAS Number
[2636771-29-2]
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Molecular Formula
C21H25N5S
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Molecular Weight
379.52
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Smiles
NCC1CCN(CC1)C2=NC(C3=CC=NC=C3)=NC4=C2C5=C(S4)CCCC5
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Target
PKC
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Isoform
PKC
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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PKC-IN-4 [CAS 2636771-29-2]
PKC-IN-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.