PMEG-DP (disodium)

PMEG-DP disodium is a potent DNA polymerase inhibitor (IC50=2.5 μM), especially for DNA polymerase α and δ. PMEG-DP disodium acts as an active metabolite of G-9191, which effectively inhibits the growth of papillomavirus (HPV) -infected cell lines. PMEG-DP disodium can be used in the study of HPV-related diseases[1].

C8H12N5Na2O11P3

493.11

O=C1N=C(NC2=C1N=CN2CCOCP(O)(OP(O)(OP(O[Na])(O[Na])=O)=O)=O)N

DNA/RNA Synthesis

Room temperature