Polygalaxanthone III [CAS 162857-78-5]

Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM[1].

[162857-78-5]

C25H28O15

568.48

COC1=C(O)C=C(OC(C=C(O)C([C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]3OC[C@@](CO)(O)[C@H]3O)O2)=C4O)=C4C5=O)C5=C1

Cytochrome P450

CYP2

99.28

DMSO : 250 mg/mL (ultrasonic)

4°C (Powder, protect from light)

Room Temperature

H302

H302