Pomaglumetad methionil [CAS 956385-05-0]

Pomaglumetad methionil (LY2140023 hydrate) is an oral methionine prodrug of the potent specific mGlu2/3 receptor agonist LY404039. Pomaglumetad methionil is well-tolerated and has a distinct safety profile, and can be used for schizophrenia[1][2].

[956385-05-0]

C12H20N2O8S2

384.43

O=C([C@]1(NC([C@@H](N)CCSC)=O)CS([C@@]2([H])[C@H](C(O)=O)[C@@]12[H])(=O)=O)O.O

MGluR

MGluR2; mGluR3

10 mM in DMSO

Room temperature

H312-H361-H372

P260-P264-P270-P280-P302+P352-P362+P364-P405-P501