Pomalidomide-CO-C7-NH-CO-C3-COOH

Pomalidomide-CO-C7-NH-CO-C3-COOH is a conjugate of a ligand for E3 ligase and a linker. Pomalidomide-CO-C7-NH-CO-C3-COOH can be used for synthesis of PROTAC degrader ARM165.

C26H32N4O8

528.55

O=C(O)CCCC(NCCCCCCCC(NC1=CC=CC2=C1C(N(C2=O)C3CCC(NC3=O)=O)=O)=O)=O

E3 Ligase Ligand-Linker Conjugates

Room temperature