PPNDS (tetrasodium) [CAS 1021868-77-8]

PPNDS tetrasodium is a selective and competitive meprin β inhibitor (IC50: 80 nM, Ki: 8 nM), and also inhibits ADAM10 (IC50: 1.2 μM) . PPNDS tetrasodium is also a P2X1 receptor antagonist. PPNDS is an agonist for the ATP receptor of Paramecium. PPNDS tetrasodium potently inhibits polymerases from viruses. PPNDS tetrasodium can be used in the research of infection and cancers[1][3][4].

[1021868-77-8]

C18H11N4Na4O14PS2

694.36

O=CC1=C(C(C)=NC(/N=N/C2=CC(S(=O)(O[Na])=O)=C(C=C([N+]([O-])=O)C=C3S(=O)(O[Na])=O)C3=C2)=C1COP(O[Na])(O[Na])=O)O

MMP; P2X Receptor

ADAM10; P2X1 Receptor

96.39

H2O : 37.5 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C (Powder, sealed storage, away from moisture)

Blue Ice