PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC50 values of 22 μM and 6.5 μM, respectively[1]. PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
[206052-01-9]
Molecular Formula
C15H18O3
Molecular Weight
246.3
Smiles
C#CCOC1=CC=CC=C1CCCCCC(O)=O
Target
COX; Cytochrome P450
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)