Pregnenolone 16α-carbonitrile [CAS 1434-54-4]

Name: Pregnenolone 16α-carbonitrile [CAS 1434-54-4]
Brand: QuantiMol
SKU: QM-0143721-01
Price: 78.82 GBP
Availability: InStock

Size 25 mg 10 mM - 1 mL 50 mg 100 mg

SKU:QM-0143721-01

£78.82 GBP

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Product Details

Description
Pregnenolone 16α-carbonitrile is an orally active prototypical and effective rodent-PXR activator. Pregnenolone 16α-carbonitrile, a synthetic steroid, induces cytochrome P450 3A expression. Pregnenolone 16α-carbonitrile exhibits increased resistance to subsequent stressful insults[1][2][3].
CAS Number
[1434-54-4]
Molecular Formula
C22H31NO2
Molecular Weight
341.49
Smiles
C[C@@]12[C@](C[C@H]([C@@H]2C(C)=O)C#N)([H])[C@@]3([H])[C@]([C@@]4(C(C[C@H](CC4)O)=CC3)C)([H])CC1
Target
Cytochrome P450; Pregnane X Receptor (PXR)
Isoform
CYP2; CYP3
Purity
98.48
Solubility
DMSO : 20 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years (Powder)
Shipping Conditions
Blue Ice

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Variant	Variant total	Quantity	Price	Variant total
25 mgQM-0143721-01	25 mgQM-0143721-01 £78.82/ea	£0.00	Quantity	£78.82/ea	£0.00

10 mM - 1 mLQM-0143721-02	10 mM - 1 mLQM-0143721-02 £89.13/ea	£0.00	Quantity	£89.13/ea	£0.00

50 mgQM-0143721-03	50 mgQM-0143721-03 £118.38/ea	£0.00	Quantity	£118.38/ea	£0.00

100 mgQM-0143721-04	100 mgQM-0143721-04 £212.81/ea	£0.00	Quantity	£212.81/ea	£0.00

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Pregnenolone 16α-carbonitrile is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.