Pregnenolone monosulfate [CAS 1247-64-9]
Pregnenolone monosulfate [CAS 1247-64-9]
SKU:QM-0160060-01
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Product Details
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Description
Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels[3].
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CAS Number
[1247-64-9]
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Molecular Formula
C21H32O5S
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Molecular Weight
396.54
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Smiles
CC([C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OS(=O)(O)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
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Target
Autophagy; Cannabinoid Receptor; Endogenous Metabolite; TRP Channel
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Isoform
CB1; Human Endogenous Metabolite
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Purity
99.96
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Solubility
DMSO : 62.5 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Pregnenolone monosulfate [CAS 1247-64-9]
Pregnenolone monosulfate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.