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Prexasertib [CAS 1234015-52-1]

Prexasertib [CAS 1234015-52-1]

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QM-0154886-01

£113.88 GBP
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Product Details

  • Description

    Prexasertib (LY2606368) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of 50=8 nM) and RSK1 (IC50=9 nM) . Prexasertib causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib shows potent anti-tumor activity[1][2].

  • CAS Number

    [1234015-52-1]

  • Molecular Formula

    C18H19N7O2

  • Molecular Weight

    365.39

  • Smiles

    NCCCOC(C=CC=C1OC)=C1C2=CC(NC3=NC=C(C#N)N=C3)=NN2

  • Target

    Apoptosis; Checkpoint Kinase (Chk)

  • Isoform

    Chk1; Chk2

  • Purity

    98.75

  • Solubility

    DMSO : 16.67 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
1 mgQM-0154886-01
1 mgQM-0154886-01
£113.88/ea		 £0.00
£113.88/ea £0.00
5 mgQM-0154886-02
5 mgQM-0154886-02
£226.18/ea		 £0.00
£226.18/ea £0.00
10 mM - 1 mLQM-0154886-03
10 mM - 1 mLQM-0154886-03
£271.13/ea		 £0.00
£271.13/ea £0.00
10 mgQM-0154886-04
10 mgQM-0154886-04
£376.83/ea		 £0.00
£376.83/ea £0.00
50 mgQM-0154886-05
50 mgQM-0154886-05
£928.45/ea		 £0.00
£928.45/ea £0.00
100 mgQM-0154886-06
100 mgQM-0154886-06
£1,215.18/ea		 £0.00
£1,215.18/ea £0.00
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Prexasertib [CAS 1234015-52-1]

Prexasertib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.