PRMT5-MTA-IN-6

Size 1 Each

SKU:QM-0012731

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Product Details

Description
PRMT5-MTA-IN-6 (Compound 31) is a selective MTA-cooperative PRMT5 inhibitor. PRMT5-MTA-IN-6 exhibits potent inhibitory activity against PRMT5MTA (IC50: 6.6 nM) . PRMT5-MTA-IN-6 selectively inhibits the growth of MTAP-deleted HCT-116 cells (IC50: 319 nM) . PRMT5-MTA-IN-6 can be used in the research of MTAP-deleted tumors[1].
Molecular Formula
C26H26N6O2
Molecular Weight
454.52
Smiles
NCC1=NNC(C2=CC=C(C=C21)C3=C4N(CCN4N=C3)CC5=CC(C6CC6)=CC7=C5OCC7)=O
Target
Histone Methyltransferase
Shipping Conditions
Room temperature

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PRMT5-MTA-IN-6 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.