Pro8-Oxytocin (TFA)

Pro8-Oxytocin TFA is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin TFA produce a less efficacious response than Vasopressin (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a[1].

C42H62N12O12S2.xC2HF3O2

O=C(N1[C@@H](CCC1)C(NCC(N)=O)=O)[C@H]2N(CCC2)C([C@H]3NC([C@@H](NC([C@@H](NC([C@](NC([C@@H](NC([C@H](CSSC3)N)=O)CC4=CC=C(C=C4)O)=O)([H])[C@@H](C)CC)=O)CCC(N)=O)=O)CC(N)=O)=O)=O.OC(C(F)(F)F)=O.[x]

Oxytocin Receptor

99.68

10 mM in DMSO

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice