PROTAC Aster-A degrader-1

PROTAC Aster-A degrader-1 (compound NGF3) is a degrader of the sterol transport protein Aster-A. PROTAC Aster-A degrader-1 can be used as a fluorescence probe. (Red: Aster-A inhibitor, black: linker, Blue: E3 ligase ligand) [1].

C42H51N7O10S

845.96

O=C(NC1=NC2=C(CN(C(OC(C)(C)C)=O)CC2)S1)C3=CC=C(C(NCCCOCCCCOCCCNC4=CC(C(N(C5CCC(NC5=O)=O)C6=O)=O)=C6C=C4)=O)C=C3

PROTACs

10 mM in DMSO

Room temperature