PROTAC BRM/BRG1 degrader-2 [CAS 2933124-32-2]

PROTAC BRM/BRG1 degrader-2 (Example.004) is a PROTAC BRM/BRG1 degrader (DC50: 50: 15 nM for A549). Blue: E3 ligase ligand , Black: linker (HY-168249), Pink: BRM/BRG1 inhibitor (HY-168248).

[2933124-32-2]

C50H60N12O5S

941.15

NC(C1=C2C=C(C3=C(O)C=CC=C3)N=N1)=NN2C(CC4)CCN4C5=NC=C([C@H]6CC[C@H](C(N[C@@H](C(C)(C)C)C(N7C[C@H](O)C[C@H]7C(N[C@H](C8=CC=C(C9=C(C)N=CS9)C=C8)C)=O)=O)=O)CC6)C=N5

Epigenetic Reader Domain; PROTACs

Room temperature