PROTAC ER Degrader-4 [CAS 2361114-15-8]

Name: PROTAC ER Degrader-4 [CAS 2361114-15-8]
Brand: QuantiMol
SKU: QM-0145020-01
Price: 497.12 GBP
Availability: InStock

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SKU:QM-0145020-01

£497.12 GBP

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Product Details

Description
PROTAC ER Degrader-4 is a von Hippel-Lindau-based PROATC estrogen receptor (ER) degrader, binding to ER with an IC50 of 0.8 nM. PROTAC ER Degrader-4 induces ER degradation in MCF-7 cells with an IC50 of 0.3 nM[1].
CAS Number
[2361114-15-8]
Molecular Formula
C53H67F3N6O8S
Molecular Weight
1005.19
Smiles
CC(C)(F)CN1[C@H](C2=C(C=C(OCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N3[C@@H](C[C@@H](O)C3)C(N[C@H](C4=CC=C(C5=C(N=CS5)C)C=C4)C)=O)=O)=O)C=C2F)F)C6=C(C7=CC=CC=C7N6)C[C@H]1C
Target
Estrogen Receptor/ERR; PROTACs
Isoform
Estrogen receptor; von Hippel-Lindau (VHL)
Purity
98.78
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
-20°C (Powder, stored under nitrogen)
Shipping Conditions
Blue Ice
Hazard Statement
H315, H319, H320
Precautions
H315, H319, H320

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0145020-01	1 mgQM-0145020-01 £497.12/ea	£0.00	Quantity	£497.12/ea	£0.00

5 mgQM-0145020-02	5 mgQM-0145020-02 £1,166.59/ea	£0.00	Quantity	£1,166.59/ea	£0.00

10 mgQM-0145020-03	10 mgQM-0145020-03 £1,870.07/ea	£0.00	Quantity	£1,870.07/ea	£0.00

50 mgQM-0145020-04	50 mgQM-0145020-04 £5,873.49/ea	£0.00	Quantity	£5,873.49/ea	£0.00

100 mgQM-0145020-05	100 mgQM-0145020-05 £9,362.98/ea	£0.00	Quantity	£9,362.98/ea	£0.00

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PROTAC ER Degrader-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.