PROTAC IRAK4 degrader-1 [CAS 2360533-90-8]

PROTAC IRAK4 degrader-1 (compound I-210) is a Cereblon-based IRAK4 PROTAC. PROTAC IRAK4 degrader-1 is composed of IRAK4 ligand (red part) PROTAC IRAK4 ligand-1 , E3 ligase ligand (blue part) Pomalidomide (HY-10984), and PROTAC linker (black part) AM-Imidazole-PA-Boc (HY-129968).

[2360533-90-8]

C44H39F3N12O7

904.85

O=C(C1=CC=C(N2C=C(NC(C3=COC(C4=CC=NC(NCC5CC5)=C4)=N3)=O)C(C(F)(F)F)=N2)C=C1)NCCCN(C=N6)C=C6CNC7=C8C(C(N(C9C(NC(CC9)=O)=O)C8=O)=O)=CC=C7

IRAK; PROTACs

Cereblon; IRAK4

99.77

DMSO : 180 mg/mL (ultrasonic)

-20°C (Powder, sealed storage, away from moisture)

Blue Ice