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SKU:QM-0146584-01
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PROTAC KRAS G12C degrader-1 is a Cereblon-based KRASG12C PROTAC degrader. PROTAC KRAS G12C degrader-1 induces CRBN/ KRASG12C dimerization and degrades GFP- KRASG12C in reporter cells[1].
[2984236-79-3]
C50H54ClFN8O6
917.47
OC1=CC2=C(C(C3=C(C4=C(C=C3Cl)C(N5CCN(CC5)C(C=C)=O)=NC(NCCCCCCCCCCCCNC6=C(C7=CC=C6)C(N(C7=O)C8CCC(NC8=O)=O)=O)=N4)F)=C1)C=CC=C2
PROTACs; Ras
Cereblon; K-Ras
99.15
DMSO : 100 mg/mL (ultrasonic)
-20°C, 3 years (Powder)
Blue Ice
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PROTAC KRAS G12C degrader-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.