PROTAC PTPN2 degrader-2 (TFA) [CAS 2912307-39-0]

PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent PTPN2 degrader with potential for studying cancer or metabolic diseases[1].

[2912307-39-0]

C51H50ClF3N6O13S2

1111.55

O=C1C2=C3C(N1[C@@H]4C(NC(CC4)=O)=O)=CC=C(C5CCN(CC5)C(NC6=CC(CS(=O)(N7C(C)(C[C@H](CC7)NC8=CC(C9=C(C(OCC(O)=O)=C(S9)C(O)=O)Cl)=CC=C8)C)=O)=CC=C6)=O)C3=CC=C2.OC(C(F)(F)F)=O

Phosphatase; PROTACs

10 mM in DMSO

Room temperature