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PROTAC Sirt2 Degrader-1 [CAS 2098487-75-1]

PROTAC Sirt2 Degrader-1 [CAS 2098487-75-1]

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SKU:QM-0083438-01

£614.98 GBP
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  • Description

    PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a bona fide Cereblon ligand for E3 ubiquitin ligase. PROTAC Sirt2 Degrader-1 shows an IC50 of 0.25 μM for Sirt2, with no effect on Sirt1/Sirt3 (IC50s>100 μM) [1].

  • CAS Number

    [2098487-75-1]

  • Molecular Formula

    C40H40N10O8S2

  • Molecular Weight

    852.94

  • Smiles

    O=C(N(C(CCC1=O)C(N1)=O)C2=O)C(C2=CC=C3)=C3OCC(NCCCCN4C=C(COC5=CC(CC6=CN=C(NC(CSC7=NC(C)=CC(C)=N7)=O)S6)=CC=C5)N=N4)=O

  • Target

    PROTACs; Sirtuin

  • Isoform

    SIRT2

  • Purity

    98.71

  • Solubility

    DMSO : ≥ 100 mg/mL

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice

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Variant Variant total Quantity Price Variant total
5 mgQM-0083438-01
5 mgQM-0083438-01
£614.98/ea
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£614.98/ea £0.00
10 mgQM-0083438-02
10 mgQM-0083438-02
£953.96/ea
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£953.96/ea £0.00
25 mgQM-0083438-03
25 mgQM-0083438-03
£1,913.81/ea
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£1,913.81/ea £0.00
50 mgQM-0083438-04
50 mgQM-0083438-04
£3,037.68/ea
£0.00
£3,037.68/ea £0.00
100 mgQM-0083438-05
100 mgQM-0083438-05
£4,820.09/ea
£0.00
£4,820.09/ea £0.00

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PROTAC Sirt2 Degrader-1 [CAS 2098487-75-1]

PROTAC Sirt2 Degrader-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.